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HRID250645

反应详情

EQUATION

反应方程式

HRID 250645 的结构方程式

REACTANTS

反应物

6
结构：c1cnc2[nH]ccc2c1
HCID9222

1H-Pyrrolo[2,3-b]pyridine

C7H6N2

结构：FC(F)(F)CI
HCID67709

1,1,1-Trifluoro-2-iodoethane

C2H2F3I

结构：Fc1cc(Cl)ccc1CBr
HCID2736551

1-(bromomethyl)-4-chloro-2-fluorobenzene

C7H5BrClF

结构：CCC1COC(Cc2ccc(OC)cc2)=N1
HCID3041214

4-Ethyl-2-[(4-methoxyphenyl)methyl]-4,5-dihydro-1,3-oxazole

C13H17NO2

结构：COc1cnc2[nH]ccc2c1
HCID10307871

5-Methoxy-7-azaindole

C8H8N2O

结构：CCOc1c(OCc2ccc(Cl)cc2F)cccc1C(=O)c1c[nH]c2ncc(OC)cc12
HCID58086972

未命名化合物

PRODUCTS

生成物

1
结构：CCOc1c(Cc2c[nH]c3ncccc23)cccc1OCc1ccc(Cl)cc1
HCID58087711

未命名化合物

PROCEDURE

实验过程

were prepared following the protocol of Scheme 71, substituting iodoethane with iodomethane in Step 3 to provide P-1891, or substituting iodoethane with 2-iodo-1,1,1-trifluoroethane in Step 3 to provide P-2076, or substituting 4-chlorobenzyl bromide 557 with 4-chloro-2-fluoro-benzyl bromide in Step 1 and 7-azaindole 94 with 5-methoxy-7-azaindole in Step 4 to provide P-2016. MS (ESI) [M+H+]+=393.4 (P-1891), 461.08 (P-2076), and 455.2 (P-2016).

WORKUP

后处理

  1. customto provide P-2076
  2. customto provide P-2016