Ammonium formate → HCID 178448786, compound

Participants

Reaction Conditions

Reaction Steps

Add ammonium formate (0.6 g, 9.6 mmol) followed by palladium on carbon (0.05 g, 0.48 mmol) to a solution of 2-(2,6-difluorophenyl-4-phenyl-5-(3-(isobutyl)amino-4-nitrophenyl)imidazole (1.0 g, 2.4 mmol) in 8 mL ethanol, and then heat the mixture to 60° C. for 3 hours. Cool the reaction mixture to room temperature, filter through celite, and concentrate the filtrate under reduced pressure to provide the title compound (0.99 g, 2.37 mmol)

Provenance & Evidence