HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetone → HCID 22565513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetone | HCID 6571 | — |
| Reactant | (+/-)-8-Methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carbothiohydrazide | HCID 12137411 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22565513 | HCID 22565513 | 67% |
Reaction Steps
A mixture of 1.00 g (2.50 mmol) of the starting material XVIII, 20 ml of dimethylformamide and 0.57 g (6.16 mmol) of chloroacetone was stirred at room temperature for 2 h. After dilution with water the precipitated crystals were filtered off and purified by refluxing in ethyl acetate to yield 0.73 g (67%) of the title compound; Mp.: 203-204° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858605B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-d491ed2a08a842f5ac686ac32ab4b803 |
| Source note | uspto-grants-2005_02 |