HCID 67272952, compound → Ethyl 3-(3'-methylaminobiphenyl-4-yl)propanoate

Participants

Reaction Steps

A solution of 1.7 g (6.0 mmol) of ethyl (E)-3-(3′-methylaminobiphenyl-4-yl)acrylate in 25 ml of methanol is stirred for 12 hours at room temperature in the presence of 300 mg (18% by mass) of 10% palladium-on-charcoal under a hydrogen atmosphere. The palladium is filtered off and the solvent is evaporated off. 1.52 g of ethyl 3-(3′-methylaminobiphenyl-4-yl)propanoate are obtained. Yield=90%

Provenance & Evidence