Triethylamine → HCID 131724742, compound

Participants

Role	Name	HCID	Charge
Reactant	Triethylamine	HCID 8471	—
Reactant	Methanesulfonyl chloride	HCID 31297	—
Reactant	1-{6-[(4-Nitrophenyl)-(pyrimidin-2-yl-hydrazono)-methyl]-benzo-1,3-dioxol-5-yl}-propan-2-ol	HCID 86593816	—
Solvent	Dichloromethane	HCID 6344	—
Product	HCID 131724742	HCID 131724742	54%

Reaction Conditions

Temperature	0 °C

Reaction Steps

2.35 g (5.58 mmol) of the compound prepared in Step A was dissolved in 50 ml of dry dichloromethane. The solution was cooled to 0° C. and after addition of 2.1 ml (15.07 mmol) of triethylamine 0.87 ml (11.22 mmol) of methanesulfonyl chloride was added over a period of 20 min, then the mixture was stirred at room temperature for 3 h. After washing with water it was dried and concentrated to yield 2.69 g (54%) of the title compound as an intermediate; Mp.: 122-124° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06858605B2
Source dataset	uspto-grants-2005_02
ORD ID	ord-c3be713337a24650838c1b460b6c0e30
Source note	uspto-grants-2005_02