HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium triacetoxyborohydride → [3-(3,4-Dihydro-2H-quinolin-1-yl)-pyridin-2-ylmethyl]-(3,5-dimethyl-pyridin-2-ylmethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | C-[3-(3,4-dihydro-2H-quinoline-1-yl)pyridine-2-yl]methylamine | HCID 67271944 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | 3,5-Dimethylpyridine-2-carbaldehyde | HCID 18731683 | — |
| Product | [3-(3,4-Dihydro-2H-quinolin-1-yl)-pyridin-2-ylmethyl]-(3,5-dimethyl-pyridin-2-ylmethyl)-amine | HCID 67272814 | — |
Reaction Steps
Using General Procedure B: Reaction of C-[3-(3,4-dihydro-2H-quinoline-1-yl)pyridine-2-yl]methylamine in CH2Cl2 and 3,5-Dimethyl-pyridine-2-carbaldehyde with NaBH(OAc)3 gave [3-(3,4-Dihydro-2H-quinolin-1-yl)-pyridin-2-ylmethyl]-(3,5-dimethyl-pyridin-2-ylmethyl)-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863293B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-d11c6a2637fe4151a5ffb199321e18ca |
| Source note | uspto-grants-2011_01 |