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HRID251106

反应详情

EQUATION

反应方程式

HRID 251106 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)NCCCCN
HCID4351

未命名化合物

结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：CC(C)(C)OC(=O)Nc1cccnc1C=O
HCID10911130

tert-Butyl (2-formylpyridin-3-yl)carbamate

C11H14N2O3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NCCCCNCc1ncccc1NC(=O)OC(C)(C)C
HCID67272833

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Using General Procedure B: Reaction of (4-Aminobutyl)-carbamic acid tert-butyl ester and (2-formylpyridin-3-yl)carbamic acid tert-butyl ester in MeOH with NaBH4 gave {2-[(4-tert-butoxycarbonylamino-butylamino)-methyl]-pyridin-3-yl}-carbamic acid tert-butyl ester as a clear residue. 1H NMR (CDCl3): δ 1.44 (s, 9H), 1.53 (s, 9H), 1.55 (m, 4H), 2.67 (m, 2H), 3.13 (m, 2H), 4.07 (s, 2H), 4.53 (m, 1H), 7.15 (dd, 1H, J=6.3 Hz), 8.11 (dd, 1H, J=6.3 Hz), 8.33 (d, 1H, J=9 Hz), 10.09 (s, 1H).