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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 251207Generated: November 1, 2026

Sodium triacetoxyborohydride → (3,5-Dimethyl-pyridin-2-ylmethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine

https://huagongshe.com/reaction/251207

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium triacetoxyborohydrideHCID 5049666—
Reactant8-Amino-5,6,7,8-tetrahydroquinolineHCID 11355564—
Reactant3,5-Dimethylpyridine-2-carbaldehydeHCID 18731683—
SolventDichloromethaneHCID 6344—
Product(3,5-Dimethyl-pyridin-2-ylmethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amineHCID 67271882—

Reaction Steps

Using General Procedure B: Reaction of 5,6,7,8-Tetrahydro-quinolin-8-ylamine and 3,5-dimethyl-pyridine-2-carboxaldehyde with NaBH(OAc)3 in CH2Cl2 gave (3,5-Dimethyl-pyridin-2-ylmethyl)-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07863293B2
Source datasetuspto-grants-2011_01
ORD IDord-d84b5b62cc8840e79f8e82850d72ccad
Source noteuspto-grants-2011_01