反应详情

温度

0 °C

5 g (19.6 mmol) of methyl 3,3-diphenyl-2,3-epoxypropionate were dissolved in 50 ml of absolute methanol and, at 0° C., 0.1 ml of boron trifluoride etherate was added. The mixture was stirred at 0° C. for 2 h and at room temperature for a further 12 h. The solvent was distilled out, the residue was taken up in ethyl acetate, washed with sodium bicarbonate solution and water and dried over magnesium sulfate. After removal of the solvent by distillation there remained 5.5 g (88%) of a pale yellow oil.

1. distillationThe solvent was distilled out
2. washwashed with sodium bicarbonate solution and water
3. dry with materialdried over magnesium sulfate
4. customAfter removal of the solvent
5. distillationby distillation there remained 5.5 g (88%) of a pale yellow oil