HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ninhydrin → Afegostat
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ninhydrin | HCID 10236 | — |
| Reactant | isopropanol water NH4OH | HCID 19893943 | — |
| Product | Afegostat | HCID 447607 | — |
Reaction Steps
TLC was performed on the different fractions (silica gel, isopropanol:water:NH4OH (7:2:1) and detection was via imino sugar and ninhydrin spray. Fractions testing positive with the imino-sugar sprays were analyzed to determine purity, then combined and lyophilized for 72 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863453B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-b34faf392972407d9d60c6902f4f0697 |
| Source note | uspto-grants-2011_01 |