Boronic Acid → HCID 178440403, compound

HRID 251585Notes

Reaction equation

HRID 251585 reaction equation
Br[C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:11]([CH3:13])[CH3:12])=[N:5][NH:6]2.[BH:14]([OH:16])[OH:15]>>[CH:11]([C:4]1[C:3]2[C:2]([B:14]([OH:16])[OH:15])=[CH:10][CH:9]=[CH:8][C:7]=2[NH:6][N:5]=1)([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 1784404044-Bromo-3-isopropyl-1H-indazole

Product 1

HCID 178440403HCID 178440403, compound

Procedure

4-Bromo-3-isopropyl-1H-indazole is converted to the corresponding boronic acid following analogous procedures to that given in the preceding example. 1H NMR (CD3OD) 7.44 (d, 1H), 7.32 (t, 1H), 7.05 (d, 1H), 3.56 (m, 1H), 1.38 (d, 6H). LCMS (m/z): 205.45 (MH)+

Sources & evidence

ORD record
ord-4284e4bf6d974833963dce462c66b006
Source dataset
uspto-grants-2011_01
Patent number
US07863454B2

Reaction notes

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