Thionyl Chloride → HCID 66993803, compound

HRID 251618Notes

Reaction equation

HRID 251618 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH2:9][CH3:10])[C:4]=1[C:11]1[N:16]=[C:15]([CH3:17])[C:14]([CH2:18]O)=[C:13]([O:20][CH2:21][CH3:22])[CH:12]=1)[CH3:2].O=S(Cl)[Cl:25]>C(Cl)Cl>[Cl:25][CH2:18][C:14]1[C:15]([CH3:17])=[N:16][C:11]([C:4]2[C:3]([CH2:1][CH3:2])=[CH:8][CH:7]=[CH:6][C:5]=2[CH2:9][CH3:10])=[CH:12][C:13]=1[O:20][CH2:21][CH3:22]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 59678289HCID 59678289, compound

Product 1

HCID 66993803HCID 66993803, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of [6-(2,6-diethyl-phenyl)-4-ethoxy-2-methyl-pyridin-3-yl]-methanol (1.8 g) and SOCl2 (2 mL) in CH2Cl2 (10 mL) is stirred at room temperature for one hour. The volatile materials are removed in vacuo to give 3-chloromethyl-6-(2,6-diethyl-phenyl)-4-ethoxy-2-methyl-pyridine.

Workup

  1. customThe volatile materials are removed in vacuo

Sources & evidence

ORD record
ord-494b63116dae4dd68e00e2a7558da19a
Source dataset
uspto-grants-2011_01
Patent number
US07863454B2

Reaction notes

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