HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-(1-Chlorobutyl)-2-(2,6-diethyl-phenyl)-4-ethoxy-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-[6-(2,6-Diethyl-phenyl)-4-ethoxy-pyridin-3-yl]-butan-1-ol | HCID 59678316 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-(1-Chlorobutyl)-2-(2,6-diethyl-phenyl)-4-ethoxy-pyridine | HCID 66993937 | — |
Reaction Steps
A mixture of 1-[6-(2,6-diethyl-phenyl)-4-ethoxy-pyridin-3-yl]-butan-1-ol (29 mg), and SOCl2 (0.2 mL) in CH2Cl2 (1 mL) is stirred at room temperature for one hour. The volatile materials are removed in vacuo to give 5-(1-chloro-butyl)-2-(2,6-diethyl-phenyl)-4-ethoxy-pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863454B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-e963a363e6224026ac78512496738ed2 |
| Source note | uspto-grants-2011_01 |