反应详情

温度

130 °C

In a 300 mL recovery flask, 75.0 g of 1-bromoadamantane (349 mmol), 9.58 g of 1,3-dihydroxybenzene (87.0 mmol), 25 mL of toluene and a stirrer were charged and agitated at 130° C. for 24 hours under nitrogen flow. Solvent was removed therefrom under reduced pressure to obtain solid. The solid was purified by column chromatography, thus obtaining 23.0 g of 4,6-di(1-adamantyl)-1,3-dihydroxybenzene (60.8 mmol; yield: 69.9%).

1. customSolvent was removed
2. customunder reduced pressure to obtain solid
3. customThe solid was purified by column chromatography