HCID 86623819, compound → HCID 67506048, compound

HRID 251713Notes

Reaction equation

HRID 251713 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:76]=[CH:77][C:78]=1[N+:79]([O-])=O)[O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2([C:52]3[CH:57]=[CH:56][C:55]([O:58][C:59]4[CH:64]=[CH:63][C:62]([N+:65]([O-])=O)=[C:61]([O:68]CC5C=CC=CC=5)[CH:60]=4)=[CH:54][CH:53]=3)[C:31]3[CH:30]=[C:29]([C:32]45[CH2:41][CH:36]6[CH2:37][CH:38]([CH2:40][CH:34]([CH2:35]6)[CH2:33]4)[CH2:39]5)[CH:28]=[CH:27][C:26]=3[C:25]3[C:20]2=[CH:21][C:22]([C:42]24[CH2:51][CH:46]5[CH2:47][CH:48]([CH2:50][CH:44]([CH2:45]5)[CH2:43]2)[CH2:49]4)=[CH:23][CH:24]=3)=[CH:15][CH:14]=1)C1C=CC=CC=1.C12(C3C=C(C45CC6CC(CC(C6)C4)C5)C(OC4C=CC([N+]([O-])=O)=C(OCC5C=CC=CC=5)C=4)=CC=3OC3C=CC([N+]([O-])=O)=C(OCC4C=CC=CC=4)C=3)CC3CC(CC(C3)C1)C2>>[NH2:65][C:62]1[CH:63]=[CH:64][C:59]([O:58][C:55]2[CH:56]=[CH:57][C:52]([C:19]3([C:16]4[CH:17]=[CH:18][C:13]([O:12][C:11]5[CH:76]=[CH:77][C:78]([NH2:79])=[C:9]([OH:8])[CH:10]=5)=[CH:14][CH:15]=4)[C:20]4[CH:21]=[C:22]([C:42]56[CH2:43][CH:44]7[CH2:50][CH:48]([CH2:47][CH:46]([CH2:45]7)[CH2:51]5)[CH2:49]6)[CH:23]=[CH:24][C:25]=4[C:26]4[C:31]3=[CH:30][C:29]([C:32]35[CH2:39][CH:38]6[CH2:37][CH:36]([CH2:35][CH:34]([CH2:40]6)[CH2:33]3)[CH2:41]5)=[CH:28][CH:27]=4)=[CH:53][CH:54]=2)=[CH:60][C:61]=1[OH:68]

Participants

3

Reactant 2

HCID 86623819HCID 86623819, compoundHCID 86630167HCID 86630167, compound

Product 1

HCID 67506048HCID 67506048, compoundYield 88.7%

Procedure

Next, a synthesis was performed in the same condition as in Synthesis example 1 except that 50.2 g of the 9,9-bis(4-(3-benzyloxy-4-nitrophenoxy)-phenyl)-2,7-di(1-adamantyl)-fluorene obtained above (46.8 mmol) was used in place of 39.0 g of 4,6-di(1-adamantyl)-1,3-bis(3-benzyloxy-4-nitrophenoxy)benzene mmol), thus obtaining 34.6 g of 9,9-bis(4-(4-amino-3-hydroxyphenoxy)-phenyl)-2,7-di(1-adamantyl)-fluorene (41.5 mmol; yield: 88.7%).

Workup

  1. customobtained above (46.8 mmol)

Sources & evidence

ORD record
ord-9cf02eb9a43d49ebb1a57e1280887b5c
Source dataset
uspto-grants-2011_01
Patent number
US07863347B2

Reaction notes

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