HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid methylene chloride → 2-[(1S)-1-Ammonio-7-oxooctyl]-5-phenyl-1H-imidazol-1-ium bis(trifluoroacetate)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Reactant | tert-Butyl[(1S)-7-oxo-1-(5-phenyl-1H-imidazol-2-yl)octyl]carbamate | HCID 91226371 | — |
| Product | 2-[(1S)-1-Ammonio-7-oxooctyl]-5-phenyl-1H-imidazol-1-ium bis(trifluoroacetate) | HCID 86627948 | — |
Reaction Steps
A2 (1 eq.) was dissolved in TFA/DCM (1:1) at 0° C. The cooling bath was removed and the mixture was stirred for 60 min at RT. The solvents were removed under reduced pressure and the residue was left under high vacuum for a further 3 h. The crude amine salt A3 was used without further purification. MS (ES) C17H23N3O requires: 285, found: 286 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07863294B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-efdaf96dfecd46cb85600f4193814f42 |
| Source note | uspto-grants-2011_01 |