HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 251762Generated: October 27, 2026
Acetic Acid → 2-Bromo-1-(4-iodophenyl)ethanone
https://huagongshe.com/reaction/251762
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromo-1-(4-iodophenyl)ethanone | HCID 256572 | 102.6% |
Reaction Steps
Dissolving 20 g (81 mmol) of 4′-iodo acetophenone into 200 milliliter of acetic acid, and adding 12.8 g (81 mmol) of bromine while cooling with ice, stirred at the temperature of 15° C. for 3 hours. After the color of bromine disappeared, adding water and separating the precipitated solids by filtration, thereby obtained 27 g of crude 2-bromo-4′-iodo acetophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07867629B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-4f186ab3782a4e79825b256306f12e77 |
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| Source note | uspto-grants-2011_01 |
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