反应详情

Dissolving 2.0 g (7.3 mmol) of 6-bromo-2-phenyl-imidazo [1,2-a] pyridine, 2.5 g (11 mmol) of 10-naphthalen-2-yl-anthracene-9-boronic acid and 0.17 g of tetrakis (triphenylphosphine) palladium into 20 milliliter of 1,2-dimethoxyethane, adding 11 milliliter of 2.0M sodium carbonate aqueous solution, the resultant suspension was refluxed under heating for 7 hours. After completion of the reaction, separation with filtration was carried out and resultant crystal were washed with water and methanol, thereby obtaining 2.7 g of yellowish white solids (yield: 75%). As a result of mass spectrum (MS) analysis, the yellowish white solids were identified as the aimed substance, and it was recognized that m/e=496 for molecular weight of 496.19.

1. temperatureunder heating for 7 hours
2. customAfter completion of the reaction, separation
3. filtrationwith filtration
4. washresultant crystal were washed with water and methanol