HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 251812Generated: October 25, 2026
3-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile → 3-(6-(Methylamino)imidazo[1,2-b]pyridazin-2-yl)benzonitrile
https://huagongshe.com/reaction/251812
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile | HCID 46835564 | — |
| Reactant | Monomethylamine methanol | HCID 57454252 | — |
| Product | 3-(6-(Methylamino)imidazo[1,2-b]pyridazin-2-yl)benzonitrile | HCID 66587405 | — |
Reaction Steps
A mixture of 3-(6-chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile (0.25 mmol) and 10 mL methylamine methanol solution was heated at 125° C. in microwave synthesizer for 30 min. After purification to provide 3-(6-(methylamino)imidazo[1,2-b]pyridazin-2-yl)benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07868001B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-d13bd094e6e94c3e931b6535e20e553c |
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| Source note | uspto-grants-2011_01 |
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