HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylene oxide → 1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethyl-4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylene oxide | HCID 11208 | — |
| Reactant | 1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethylpiperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide | HCID 66859962 | — |
| Product | 1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethyl-4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrochloride | HCID 66860083 | — |
Reaction Steps
The compound is prepared in analogy to Example 89 from the compound of Example 12 and 1,2-epoxy-2-methylpropane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07867992B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-44aca59d73bd4d4992f99ce9b44abc8a |
| Source note | uspto-grants-2011_01 |