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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 251862Generated: October 27, 2026

Isobutylene oxide → 1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethyl-4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrochloride

https://huagongshe.com/reaction/251862

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutylene oxideHCID 11208—
Reactant1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethylpiperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamideHCID 66859962—
Product1-Cyclopropyl-N-(2,4-dichlorobenzyl)-7-[(3RS,5SR)-3,5-dimethyl-4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxamide hydrochlorideHCID 66860083—

Reaction Steps

The compound is prepared in analogy to Example 89 from the compound of Example 12 and 1,2-epoxy-2-methylpropane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07867992B2
Source datasetuspto-grants-2011_01
ORD IDord-44aca59d73bd4d4992f99ce9b44abc8a
Source noteuspto-grants-2011_01