HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-3,5-dibromobenzoic acid → 6,8-dibromo-2-[4-bromo-1-(3-nitro-2-pyridinyl)-1H-pyrrol-2-yl]-4H-3,1-benzoxazine-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-3,5-dibromobenzoic acid | HCID 219491 | — |
| Reactant | 2-Amino-5-chloro-3-methylbenzoic acid | HCID 11644044 | — |
| Reactant | 4-bromo-1-(3-nitro-2-pyridinyl)-1H-pyrrole-2-carboxylic acid | HCID 66854454 | — |
| Reactant | 4-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrrole-2-carboxylic acid | HCID 66854487 | — |
| Product | 6,8-dibromo-2-[4-bromo-1-(3-nitro-2-pyridinyl)-1H-pyrrol-2-yl]-4H-3,1-benzoxazine-4-one | HCID 66854303 | — |
Reaction Steps
According to the same manner as that of Reference Preparation Example 71-(5), 4-bromo-1-(3-nitro-2-pyridinyl)-1H-pyrrole-2-carboxylic acid and 2-amino-3,5-dibromobenzoic acid were used in place of 4-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrrole-2-carboxylic acid and 2-amino-5-chloro-3-methylbenzoic acid respectively to obtain 6,8-dibromo-2-[4-bromo-1-(3-nitro-2-pyridinyl)-1H-pyrrol-2-yl]-4H-3,1-benzoxazine-4-one of the formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07867949B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-e08005dcfcdc4b138fbcc960160a8154 |
| Source note | uspto-grants-2011_01 |