HCID 66854171, compound → HCID 86240147, compound

Participants

Reaction Steps

Dissolve (4,5-dichloroisothiazol-3-yl)-methanol (300 mg, 1.63 mmol) in dichloromethane (10 mL). Add pyridinium chlorochromate (703 mg, 3.26 mmol) and stir for 2 h. Pour the mixture onto a column of silica gel, eluting with dichloromethane and concentrate to give 4,5-dichloroisothiazol-3-carbaldehyde as a white solid (193 mg, 65%). 1H NMR (400 MHz, MeOH-d4) δ 9.96 (s, 1H).

Provenance & Evidence