反应详情

温度

100 °C

6-Methoxybenzo[b]thiophene (6.15 g, 37.45 mmol) and pyridine hydrochloride (18.5 g) were heated together at 210° C. for 1 h. The mixture was cooled to 100° C., diluted with water (125 mL) and extracted with dichloromethane (3×70 mL). The combined extracts were washed with water (125 mL), dried (MgSO4) and evaporated in vacuo to give the title compound (5.54 g, 98%)

1. extractionextracted with dichloromethane (3×70 mL)
2. washThe combined extracts were washed with water (125 mL)
3. dry with materialdried (MgSO4)
4. customevaporated in vacuo