3-Bromo-5-fluoropyridine → N-tert-Butyl-4-(5-fluoro-pyridin-3-yl)-3-methyl-benzenesulfonamide

Participants

Reaction Steps

This compound was prepared analogous to Example 52, starting from N-tert-butyl-3-methyl-benzenesulfonamide boronic acid (0.5 g, 1.84 mmol) and 5-bromo-3-fluoropyridine (357 mg, 2.03 mmol, 1.1 equiv.) After purification on silica-gel with n-heptane/ethyl acetate, 335 mg of the title compound were obtained as a light yellow solid MS (ES): m/e 321.1 (M−H)

Provenance & Evidence