1-Bromo-2,4,6-trifluorobenzene → HCID 66842952, compound

HRID 252333Notes

Reaction equation

HRID 252333 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH2:15])[CH:6]=[C:7]([O:12][CH3:13])[C:8]=1[CH2:9][CH2:10][CH3:11].Br[C:17]1[C:22]([F:23])=[CH:21][C:20]([F:24])=[CH:19][C:18]=1[F:25]>>[CH3:13][O:12][C:7]1[CH:6]=[C:5]([CH:14]=[CH:15][C:21]2[C:22]([F:23])=[CH:17][C:18]([F:25])=[CH:19][C:20]=2[F:24])[CH:4]=[C:3]([O:2][CH3:1])[C:8]=1[CH2:9][CH2:10][CH3:11]

Participants

3

Reactant 2

HCID 753981-Bromo-2,4,6-trifluorobenzeneHCID 66842614(3,5-Dimethoxy-4-1-propylphenyl)ethene

Product 1

HCID 66842952HCID 66842952, compoundYield 58%

Procedure

This compound was synthesized from (3,5-dimethoxy-4-1-propylphenyl)ethene and 1-bromo-2,4,6-trifluorobenzene in 58% yield in the same procedure as described in preparation of 31B. 1HNMR (CDCl3, ppm): δ 1.32 (d, J=7.0 Hz, 6H), 3.62 (qint, J=7.1 Hz, 1H), 3.89 (s, 6H), 6.73 (s, 2H), 6.79-7.55 (m, 4H).

Sources & evidence

ORD record
ord-efc1c23568dc41a28171d8a229a98eb3
Source dataset
uspto-grants-2011_01
Patent number
US07868047B2

Reaction notes

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