4-Bromopyridine-2-carbaldehyde → HCID 23149462, compound

HRID 252356Notes

Reaction equation

HRID 252356 reaction equation
[Br-].[CH3:2][O:3][CH2:4][CH2:5][CH2:6][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[Br:26][C:27]1[CH:32]=[CH:31][N:30]=[C:29]([CH:33]=O)[CH:28]=1>>[Br:26][C:27]1[CH:32]=[CH:31][N:30]=[C:29]([CH2:33][CH2:6][CH2:5][CH2:4][O:3][CH3:2])[CH:28]=1

Participants

3

Reactant 2

HCID 147614724-Bromopyridine-2-carbaldehydeHCID 21458797(3-Methoxypropyl)(triphenyl)phosphanium bromide

Product 1

HCID 23149462HCID 23149462, compound

Procedure

Analogously to residue 1a, 2,4 mmol of (3-methoxypropyl)triphenylphosphonium bromide [111088-69-8] and 1.6 mmol of 4-bromopyridine-2-carbaldehyde [131747-63-2] are reacted. The title compound (E,Z mixture) is identified on the basis of the Rf value.

Sources & evidence

ORD record
ord-3b69f6f77bfc4fbe95eab9c846764f40
Source dataset
uspto-grants-2011_01
Patent number
US07868036B2

Reaction notes

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