HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 252367Generated: October 26, 2026
Diethylether pentane → 4-(4-Methoxy-butyl)pyridin-3-ol
https://huagongshe.com/reaction/252367
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethylether pentane | HCID 21877078 | — |
| Reactant | Acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester | HCID 66889070 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-(4-Methoxy-butyl)pyridin-3-ol | HCID 23149465 | — |
Reaction Steps
A mixture of 39 mmol acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester in 20 ml acetic acid is heated to 70° C. for 30 minutes. After cooling, 75 ml of diethyl ether/pentane (1:5) is added and the precipitate is collected by filtration. The title compound is obtained from the solid by re-crystallization from toluene and identified based on its Rf value.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07868036B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-8ecbfd7d18b04774b6f5f3959e4c6088 |
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| Source note | uspto-grants-2011_01 |
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