Thiobenzoyl acetamide → HCID 178475089, compound

HRID 25239Notes

Reaction equation

HRID 25239 reaction equation
[C:1](CC(N)=O)(=S)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.Cl.[NH2:15][CH:16]([CH2:29][CH:30]1[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1)[C:17]([NH:19][C:20]1([C:27]#[N:28])[CH2:25][CH2:24][N:23]([CH3:26])[CH2:22][CH2:21]1)=[O:18]>>[C:17]([N:19]=[C:1]([NH:15][CH:16]([CH2:29][CH:30]1[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]1)[C:17]([NH:19][C:20]1([C:27]#[N:28])[CH2:21][CH2:22][N:23]([CH3:26])[CH2:24][CH2:25]1)=[O:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)(=[O:18])[CH3:16]

Participants

3

Reactant 2

HCID 12909051Thiobenzoyl acetamideHCID 225663392-amino-N-(-4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexylpropionamide bis hydrochloride salt

Product 1

HCID 178475089HCID 178475089, compound

Procedure

The title compound was prepared starting from thiobenzoyl acetamide and 2-amino-N-(4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexyl-propionamide bis hydrochloride salt according to the procedure from Example 1, step b. MS, m/z 438=M+1.

Sources & evidence

ORD record
ord-997f8642bcd44d61808ea256110e4bb0
Source dataset
uspto-grants-2005_02
Patent number
US06858623B2

Reaction notes

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