HCID 86618877, compound → HCID 66889227, compound

HRID 252395Notes

Reaction equation

HRID 252395 reaction equation
C([O:8][C:9](=[O:25])[C:10]([C:13]1[N:14](CC2C=CC=CC=2)[CH:15]=[CH:16][N:17]=1)([CH3:12])[CH3:11])C1C=CC=CC=1>C(O)C>[NH:14]1[CH:15]=[CH:16][N:17]=[C:13]1[C:10]([CH3:12])([CH3:11])[C:9]([OH:25])=[O:8]

Participants

3

Reactant 1

HCID 86618877HCID 86618877, compound

Product 1

HCID 66889227HCID 66889227, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.334 g of 2-(1-benzyl-1H-imidazol-2-yl-2-methyl-propionic acid benzyl ester are hydrogenated at 440 psi in ethanol (50 ml) at 50° C. for 24 hours. The catalyst is removed by filtration over Hyflo and the filtrate is concentrated under reduced pressure to provide the title compound which can be used without further purification.

Workup

  1. customThe catalyst is removed by filtration over Hyflo
  2. concentrationthe filtrate is concentrated under reduced pressure

Sources & evidence

ORD record
ord-1c508b1061624af592633505cfd0823a
Source dataset
uspto-grants-2011_01
Patent number
US07868036B2

Reaction notes

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