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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 25247Erstellt: 25. Oktober 2026

Pseudosaccharin chloride → HCID 178456249, Verbindung

https://huagongshe.com/reaction/25247

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPseudosaccharin chlorideHCID 64783—
Edukt2-amino-N-(-4-cyano-1-propyl-piperidin-4-yl)-3-cyclohexylpropionamide bis hydrochloride saltHCID 86585200—
ProduktHCID 178456249HCID 178456249—

Reaktionsschritte

The title compound was prepared starting from 3-chloro-benzo[d]isothiazole 1,1-dioxide and 2-amino-N-(-4-cyano-1-propyl-piperidin-4-yl)-3-cyclohexylpropionamide bis hydrochloride salt according to the procedure from Example 10, except that the compound was further purified by HPLC using a 20×250 mm C18 reverse phase column with the method being 20% acetonitrile in water to acetonitrile. MS, m/z 486=M+1.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06858623B2
Quelldatensatzuspto-grants-2005_02
ORD IDord-9a1dcfedcae24905b49ccd2068f6dddf
Quellennotizuspto-grants-2005_02