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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 252474Generated: October 25, 2026

Propiolic Acid → 1-Dodecyl-1H-1,2,3-triazole-4-carboxylic acid

https://huagongshe.com/reaction/252474

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropiolic AcidHCID 10110—
Reactant1-AzidododecaneHCID 10998318—
Product1-Dodecyl-1H-1,2,3-triazole-4-carboxylic acidHCID 63467685—

Reaction Conditions

Temperature120 °C

Reaction Steps

A mixture of propiolic acid (46 μL, 0.7419 mmol) and 1-azido-dodecane (156.8 mg, 0.7419 mmol) was heated to 120° C. in a capped vial for 14 h, to yield the title triazole as white, crystalline solid (189.3 mg, 91% yield). The product was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07868135B2
Source datasetuspto-grants-2011_01
ORD IDord-eb3be02f342142e3bc24729ff2e33713
Source noteuspto-grants-2011_01