Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pseudosaccharin chloride → HCID 178446098, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pseudosaccharin chloride | HCID 64783 | — |
| 반응물 | 2-amino-N-[3-cyano-1-(1-ethyl-propyl)-pyrrolidin-3-yl]-3-cyclohexyl-propionamide bis hydrochloride salt | HCID 86585202 | — |
| 생성물 | HCID 178446098 | HCID 178446098 | — |
반응 단계
The title compound was prepared starting from 3-chloro benzo[d]isothiazole 1,1-dioxide and 2-amino-N-[3-cyano-1-(1-ethyl-propyl)-pyrrolidin-3-yl]-3-cyclohexyl-propionamide bis hydrochloride salt according to the procedure from Example 10, except that the compound was further purified by HPLC using a 20×250 mm C18 reverse phase column with the method being 40% acetonitrile in water to acetonitrile. MS, m/z 500=M+1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858623B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-f33d14190f7641048fb9eb0b7bdfa05b |
| 출처 메모 | uspto-grants-2005_02 |