2-Amino-4,4-dimethyl-pentanoic acid(4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt → HCID 178456250, compound

HRID 25252Notes

Reaction equation

HRID 25252 reaction equation
[NH:1]=[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[NH:3]1.Cl.Cl.[C:14]([C:16]1([NH:25][C:26](=[O:34])[CH:27](N)[CH2:28][C:29]([CH3:32])([CH3:31])[CH3:30])[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH3:24])[CH2:18][CH2:17]1)#[N:15]>>[C:14]([C:16]1([NH:25][C:26](=[O:34])[CH:27]([NH:1][C:2]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[C:4](=[O:11])[N:3]=2)[CH2:28][C:29]([CH3:32])([CH3:31])[CH3:30])[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH3:24])[CH2:18][CH2:17]1)#[N:15]

Participants

3

Reactant 2

HCID 865852012-Amino-4,4-dimethyl-pentanoic acid(4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride saltHCID 1357423743-Imino-2,3-dihydroisoindol-1-one

Product 1

HCID 178456250HCID 178456250, compound

Procedure

The title compound was prepared from 3-imino-2,3-dihydro-isoindol-1-one and 2-amino-4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt according to the procedure from Example 15. MS, m/z 424.5=M+1.

Sources & evidence

ORD record
ord-0c47788f338948049fec5c8f44ca55d6
Source dataset
uspto-grants-2005_02
Patent number
US06858623B2

Reaction notes

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