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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 252658Generated: November 4, 2026

Isatin → 1-Benzylisatin

https://huagongshe.com/reaction/252658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsatinHCID 7054—
ReactantBenzyl ChlorideHCID 7503—
ReactantChloroacetanilideHCID 11485—
Product1-BenzylisatinHCID 264734—

Reaction Steps

Indoline-2,3-dione (I-D) is either N-alkylated with benzylchloride (I-E) or N-phenyl-2-chloro-acetamid (I-F) to yield the 1-benzylindoline-2,3-dione (I-G) or with the 1-phenylcarbamoylmethylindoline-2,3-dione (I-H), respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07868185B2
Source datasetuspto-grants-2011_01
ORD IDord-97ffc561bd4448a6acd34804d1ee761b
Source noteuspto-grants-2011_01