Iodoethane → HCID 67262703, compound

Participants

Reaction Steps

To a 250 mL flask were added bromotrimethylindole 2 (12 g, 50.4 mmol), acetonitrile (25 mL) and ethyl iodide (20 mL). The mixture was heated at reflux under argon for 40 h. The bulk of the volatile components were removed by distillation. The residue was triturated with ether (100 mL) to give a powder. The solid was filtered off, washed with ether (2×50 mL) and dried under high vacuum to afford 3 as a solid (17.3 g, 87%).

Provenance & Evidence