Ethyl benzoylacetate → 1-benzoyl-6-bromo-2,7-dihydro-3-methyl-2,7-dioxo-3H-dibenzo[f,ij]isoquinoline

HRID 252895Notes

Reaction equation

[CH3:1][NH:2][C:3]1[C:16]2[C:15](=O)[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8](=[O:18])[C:7]=2[C:6]([Br:19])=[CH:5][CH:4]=1.C(O[C:23](=[O:33])[CH2:24][C:25](=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)C>>[C:25]([C:24]1[C:23](=[O:33])[N:2]([CH3:1])[C:3]2[CH:4]=[CH:5][C:6]([Br:19])=[C:7]3[C:8](=[O:18])[C:9]4[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=4[C:15]=1[C:16]=23)(=[O:32])[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

Reactant 2

HCID 7170Ethyl benzoylacetate

HCID 314189,10-Anthracenedione, 1-bromo-4-(methylamino)-

Product 1

HCID 118585271-benzoyl-6-bromo-2,7-dihydro-3-methyl-2,7-dioxo-3H-dibenzo[f,ij]isoquinoline

Procedure

1-Methylamino-4-bromoanthraquinone is reacted with benzoylacetic acid ethyl ester in a solvent to obtain 1-benzoyl-6-bromo-2,7-dihydro-3-methyl-2,7-dioxo-3H-dibenzo[f,ij]isoquinoline.

Sources & evidence

ORD record: ord-1b601a0a32104752841cb1d6b28f4dfd
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07871465B2

Reaction notes

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