HuagongsheHuagongshe Chemistry Print Report · For research reference only
5',5'-dimethyl-3-nitro-6,8,9,10-tetrahydro-5H-spiro[cycloocta[b]pyridine-7,2'-[1,3]dioxane] → HCID 59295549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5',5'-dimethyl-3-nitro-6,8,9,10-tetrahydro-5H-spiro[cycloocta[b]pyridine-7,2'-[1,3]dioxane] | HCID 59295674 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | HCID 59295549 | HCID 59295549 | — |
Reaction Steps
The compound of formula (Cc), 5′,5′-dimethyl-3-nitro-6,8,9,10-tetrahydro-5H-spiro[cycloocta[b]pyridine-7,2′-[1,3]dioxane], was hydrogenated in ethanol/THF solution over 10% Pd/C for 1 hour at 40 psi to give the compound of formula (Cd), 5′,5′-dimethyl-6,8,9,10-tetrahydro-5H-spiro[cycloocta[b]pyridine-7,2′-[1,3]dioxan]-3-amine, in quantitative yield; MS (ES) 277.67 (M+2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07872000B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-7e0b8fa7dd2c44b89a7b847a2a37195a |
| Source note | uspto-grants-2011_01 |