HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 252935Generated: October 30, 2026
1,2-Dichloroethane → HCID 79046843, compound
https://huagongshe.com/reaction/252935
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | 2-Bromothiazole | HCID 76430 | — |
| Reactant | Tert-butyl 3-aminoazetidine-1-carboxylate | HCID 1516507 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 79046843 | HCID 79046843 | 11% |
Reaction Steps
A mixture of 5.0 g (29.1 mmol) of 1-Boc-3-aminoazetidine and 2.62 ml (29.1 mmol) of 2-bromothiazole was heated to 140° C. with stirring for 2 h. After cooling to RT, 800 mg (3.14 mmol, 11%) of 1-Boc-3-(thiazol-2-ylamino)azetidine were obtained from the mixture by CC (SiO2, 1 st DCE, 2nd chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07871999B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-efe394f96f034407bbf350e352421713 |
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| Source note | uspto-grants-2011_01 |
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