HCID 178507348, compound → HCID 178515210, compound

HRID 252948Notes

Reaction equation

HRID 252948 reaction equation
[C:1]1([N:7]2[C:25](=[O:26])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[CH:15][C:16]([N:19]5[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]5)=[CH:17][C:18]=4[C:9]3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NC1C=CC2NC=C3C(=O)N(C4C=CC([Cl:47])=CC=4)N=C3C=2C=1>>[Cl:47][C:4]1[CH:5]=[CH:6][C:1]([N:7]2[C:25](=[O:26])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[CH:15][C:16]([N:19]5[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]5)=[CH:17][C:18]=4[C:9]3=[N:8]2)=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 178507348HCID 178507348, compoundHCID 178515209HCID 178515209, compound

Product 1

HCID 178515210HCID 178515210, compound

Procedure

The title compound was prepared following the procedure described for 7a using 6b. 1H-NMR (DMSO-d6) δ (ppm): 3.25 (4H, br), 3.50 (4H, br), 3.75 (3H, s), 7.00 (1H, d, J=9.06 Hz), 7.40 (1H, m), 7.48 (1H, br), 7.68 (1H, d, J=9.06 Hz), 7.92 (1H, d, J=8.79 Hz), 8.05 (2H, d, J=8.79 Hz), 8.56 (1H, br), 9.12 (1H, br). m/z 380.9 (MH+).

Sources & evidence

ORD record
ord-26d294b571c641fe8eb8601f5088d99b
Source dataset
uspto-grants-2011_01
Patent number
US07872002B2

Reaction notes

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