HCID 178492053, compound → HCID 178492051, compound

HRID 252960Notes

Reaction equation

HRID 252960 reaction equation
[C:1]1([N:7]2[C:25](=[O:26])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[C:15]([N:19]5[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]5)[CH:16]=[CH:17][C:18]=4[C:9]3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NC1C=CC2C3C(C(=O)N(C4C=C[C:44]([O:47]C)=CC=4)N=3)=CNC=2C=1>>[CH3:44][O:47][C:4]1[CH:5]=[CH:6][C:1]([N:7]2[C:25](=[O:26])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[C:15]([N:19]5[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]5)[CH:16]=[CH:17][C:18]=4[C:9]3=[N:8]2)=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 178492053HCID 178492053, compoundHCID 178515224HCID 178515224, compound

Product 1

HCID 178492051HCID 178492051, compound

Procedure

The title compound was prepared following the procedure for 14a using 13c. 1H-NMR (DMSO-d6) δ (ppm): 3.04 (4H, br), 3.75 (3H, s), 3.90 (4H, br), 6.8 (1H, m), 7.26 (2H, m), 7.42 (1H, m), 7.87 (1H, d, J=8.79 Hz), 8.05 (2H, d, J=9.06 Hz), 8.62 (1H, br). m/z 376.4 (MH+).

Sources & evidence

ORD record
ord-c5e1c56af586435db0b8510b01708773
Source dataset
uspto-grants-2011_01
Patent number
US07872002B2

Reaction notes

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