(2-Chloro-4-fluoro-5(3-trifluoromethyltriazolyl)phenyl]methyl sulfide → HCID 131723750, compound

HRID 25304Notes

Reaction equation

HRID 25304 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([C:9]2[N:10]([C:14]([F:17])([F:16])[F:15])[N:11]=[N:12][CH:13]=2)=[CH:4][C:3]=1SC.ClC1C=C(F)C(C2N(C(F)(F)F)N=NC=2)=CC=1S>>[Cl:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([C:9]2[N:10]([C:14]([F:16])([F:17])[F:15])[N:11]=[N:12][CH:13]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 22567417(2-Chloro-4-fluoro-5(3-trifluoromethyltriazolyl)phenyl]methyl sulfideHCID 686593262-Chloro-4-fluoro-5(3-trifluoromethyltriazolyl)thiophenol

Product 1

HCID 131723750HCID 131723750, compoundYield 85.7%

Procedure

2.2 g (7.1 mmol) of [2-chloro-4-fluoro-5(3-trifluoromethyltriazolyl)phenyl]methyl sulfide was converted to 2-chloro-4-fluoro-5(3-trifluoromethyltriazolyl)thiophenol in the same manner as in Reference Example 1 and then to 1.8 g of 1,1′-thiodi-[2-chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)benzene (yield 85.7%) in the same manner as in Reference Example (1), which was used in Example 2 (4) as the starting material.

Sources & evidence

ORD record
ord-ee37b9d7900d43eabf7d530e6d7d02af
Source dataset
uspto-grants-2005_02
Patent number
US06858639B2

Reaction notes

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