HCID 1486231, compound → 6-Oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid

HRID 253121Notes

Reaction equation

HRID 253121 reaction equation
Cl[C:2]1[C:3]([C:15]([OH:17])=[O:16])=[N:4][N:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:6](=[O:8])[CH:7]=1>CCO.[Pd]>[O:8]=[C:6]1[N:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:4]=[C:3]([C:15]([OH:17])=[O:16])[CH:2]=[CH:7]1

Participants

4

Reactant 1

HCID 1486231HCID 1486231, compound

Product 1

HCID 167717136-Oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4-chloro-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid (100 mg, 0.4 mmol) was dissolved in 3 ml EtOH and Pd/C (25 mg) was added. A H2 balloon was attached to the reaction vessel and the mixture was stirred for 4 h. The reaction was filtered through a pad of Celite®, concentrated and used without further purification in the next reaction. MS m/z: 217(100%, M+1)).

Workup

  1. filtrationThe reaction was filtered through a pad of Celite®
  2. concentrationconcentrated
  3. customused without further purification in the next reaction

Sources & evidence

ORD record
ord-db7bff729da04337b5a045894f91f93e
Source dataset
uspto-grants-2011_01
Patent number
US07872009B2

Reaction notes

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