5-(3,4-Dimethylphenyl)furan-2-carbaldehyde → HCID 22566656, compound

Participants

Reaction Conditions

Reaction Steps

To an agitated solution of 5-(3,4-dimethylphenyl)-furan-2-carbaldehyde (0.030 g, 0.15 mmol) in EtOH (0.80 mL) was added 7,8-diamino-1-hydroxy-3-naphthoic acid dihydrochloride (0.029 g, 0.10 mmol) and sodium bisulfite (30 mg) in water (0.20 mL). The solution was heated to 60° C. and agitated overnight. The solution was cooled to room temperature, the tan precipitate was isolated by filtration and washed with water and ethyl acetate to provide the title compound (0.007 g, 15%) MS(ES) m/z 399 [M−H].

Provenance & Evidence