5,6-Diamino-4-hydroxy-2-naphthalenecarboxylic acid → HCID 22566662, compound

HRID 25326Notes

Reaction equation

HRID 25326 reaction equation
CO[C:3]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2C)=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.[NH2:18][C:19]1[C:28]([NH2:29])=[CH:27][CH:26]=[C:25]2[C:20]=1[C:21]([OH:33])=[CH:22][C:23]([C:30]([OH:32])=[O:31])=[CH:24]2.Cl.Cl.N[C:37]1C=C(S(O)(=O)=O)C2C([C:46]=1N)=C(O)C=CC=2>>[CH2:37]([C:14]1[CH:13]=[CH:12][C:11]([C:10]2[CH:9]=[CH:8][CH:7]=[C:4]([C:5]3[NH:29][C:28]4[CH:27]=[CH:26][C:25]5[C:20](=[C:21]([OH:33])[CH:22]=[C:23]([C:30]([OH:32])=[O:31])[CH:24]=5)[C:19]=4[N:18]=3)[CH:3]=2)=[CH:16][CH:15]=1)[CH3:46]

Participants

4

Reactant 3

HCID 109659775,6-Diamino-4-hydroxy-2-naphthalenecarboxylic acidHCID 118063762-Methoxy-3-(2'-methylphenyl)benzaldehydeHCID 865878481,2-Diamino-8-hydroxy-naphthalene-4-sulfonic acid dihydrochloride

Product 1

HCID 22566662HCID 22566662, compound

Procedure

Follow the procedure of example 1c) except substituting 4′-ethylbiphenyl-3-carbaldehyde for 2-methoxy-3-(2′-methyl phenyl) benzaldehyde and 5,6-diamino-4-hydroxynaphthalene-2-carboxylic acid for 3,4-diamino-5-hydroxy-1-naphthalene sulfonic acid dihydrochloride, the title compound was prepared as a solid (0.046 g, 99%). MS(ES) m/z 409 [M+H].

Sources & evidence

ORD record
ord-f2aabf5e935f4c48b491426525394b3e
Source dataset
uspto-grants-2005_02
Patent number
US06858630B2

Reaction notes

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