5,6-Diamino-4-hydroxy-2-naphthalenecarboxylic acid → HCID 22566693, compound

HRID 25328Notes

Reaction equation

HRID 25328 reaction equation
CO[C:3]1[C:10]([C:11]2C=CC=[CH:13][C:12]=2C)=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.[NH2:18][C:19]1[C:28]([NH2:29])=[CH:27][CH:26]=[C:25]2[C:20]=1[C:21]([OH:33])=[CH:22][C:23]([C:30]([OH:32])=[O:31])=[CH:24]2.Cl.Cl.N[C:37]1[CH:38]=[C:39](S(O)(=O)=O)[C:40]2[C:45]([C:46]=1N)=[C:44](O)[CH:43]=[CH:42][CH:41]=2>>[CH:37]1[C:38]2[CH2:46][C:45]3[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=3)[C:39]=2[CH:13]=[CH:12][C:11]=1[C:10]1[CH:3]=[C:4]([C:5]2[NH:29][C:28]3[CH:27]=[CH:26][C:25]4[C:20](=[C:21]([OH:33])[CH:22]=[C:23]([C:30]([OH:32])=[O:31])[CH:24]=4)[C:19]=3[N:18]=2)[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 3

HCID 109659775,6-Diamino-4-hydroxy-2-naphthalenecarboxylic acidHCID 118063762-Methoxy-3-(2'-methylphenyl)benzaldehydeHCID 865878481,2-Diamino-8-hydroxy-naphthalene-4-sulfonic acid dihydrochloride

Product 1

HCID 22566693HCID 22566693, compound

Procedure

Follow the procedure of example 1c) except substituting 3-(9H-Fluoren-2-yl)-benzaldehyde for 2-methoxy-3-(2′-methylphenyl)benzaldehyde and 5,6-diamino-4-hydroxynaphthalene-2-carboxylic acid for 3,4-diamino-5-hydroxy-1-naphthalene sulfonic acid dihydrochloride, the title compound was prepared as a solid (0.004 g, 8%). MS(ES) m/z 469 [M+H].

Sources & evidence

ORD record
ord-9f407b2605814400887d98bb0e539404
Source dataset
uspto-grants-2005_02
Patent number
US06858630B2

Reaction notes

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