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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253340Generated: October 25, 2026

3-Methoxybenzaldehyde → 4-Iodomethyl-5-ethyl-2-(3-methoxyphenyl)oxazole

https://huagongshe.com/reaction/253340

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxybenzaldehydeHCID 11569—
Reactant2,3-Pentanedione, 2-oximeHCID 6797453—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product4-Iodomethyl-5-ethyl-2-(3-methoxyphenyl)oxazoleHCID 57434506—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, 1-ethyl-1,2-propanedione-2-oxime and m-anisaldehyde gave 4-iodomethyl-5-ethyl-2-(3-methoxyphenyl)oxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872034B2
Source datasetuspto-grants-2011_01
ORD IDord-117425554f18421da3e3a612f77d03e0
Source noteuspto-grants-2011_01