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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253343Generated: October 25, 2026

4-Methylbenzaldehyde → 2-(4-Methylphenyl)-4-iodomethyl-5-methyloxazole

https://huagongshe.com/reaction/253343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
Reactant2,3-Butanedione monoximeHCID 6409633—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product2-(4-Methylphenyl)-4-iodomethyl-5-methyloxazoleHCID 21980311—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and p-tolualdehyde gave 4-iodomethyl-5-methyl-2-p-tolyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872034B2
Source datasetuspto-grants-2011_01
ORD IDord-f34cf93ca45e470aa911036979a4d46e
Source noteuspto-grants-2011_01