HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethoxy)benzaldehyde → 4-(Iodomethyl)-5-methyl-2-[3-(trifluoromethoxy)phenyl]-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethoxy)benzaldehyde | HCID 605139 | — |
| Reactant | 2,3-Butanedione monoxime | HCID 6409633 | — |
| Reactant | 4-Iodomethyl-5-phenyl-2-p-tolyloxazole | HCID 57434504 | — |
| Product | 4-(Iodomethyl)-5-methyl-2-[3-(trifluoromethoxy)phenyl]-1,3-oxazole | HCID 22493706 | — |
Reaction Steps
Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 3-trifluoromethoxybenzaldehyde gave 4-iodomethyl-5-methyl-2-(3-trifluoromethoxyphenyl)oxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07872034B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-919db855b25646dda883a690d234767f |
| Source note | uspto-grants-2011_01 |