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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253370Generated: October 29, 2026

5-isopropenyl-1H-pyrrolo[2,3-b]pyridine → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/253370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-isopropenyl-1H-pyrrolo[2,3-b]pyridineHCID 58086810—
CatalystPalladium hydroxideHCID 9942167—
SolventTetrahydrofuranHCID 8028—
Product5-isopropyl-1H-pyrrolo[2,3-b]pyridineHCID 59928720—

Reaction Steps

To 5-isopropenyl-1H-pyrrolo[2,3-b]pyridine (10, 0.080 g, 0.501 mmol) in tetrahydrofuran (5.0 mL) was added 20% palladium hydroxide on carbon (5.0 mg). The reaction was stirred under hydrogen at 40 psi for 30 minutes. The reaction mixture was filtered and concentrated to give the compound (11, 0.078 g, 96%). MS (ESI) [M+H+]+=161.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872018B2
Source datasetuspto-grants-2011_01
ORD IDord-87ff7b568543441796a15ec5091015cc
Source noteuspto-grants-2011_01