HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetonitrile → 2-(2-Amino-2-oxoethoxy)-5-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetonitrile | HCID 7856 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Benzoic acid, 5-chloro-2-hydroxy-, methyl ester | HCID 77684 | — |
| Product | 2-(2-Amino-2-oxoethoxy)-5-chlorobenzoic acid | HCID 8707311 | — |
Reaction Steps
Commercially available, methyl 5-chloro-2-hydroxybenzoate (Maybridge), potassium carbonate, 2-chloroacetonitrile (Aldrich) and sodium hydroxide were processed according to the method described for Example 130A to obtain the title compound. MS (ESI+) m/z 248 (M+H2O)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07872033B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-5f1d2577f9704028939d2a4b5ca247b4 |
| Source note | uspto-grants-2011_01 |